Kolff's first book on the artificial kidney. This was his doctoral dissertation. There were two versions published. The first was designated Proefschrift and credited Kolff as Willem Johan Kolff on the title page. It indicated on the title page that Kolff defended the dissertation on January 16, 1946. Laid in was a printing of Kolff's "Stellingen" (theses). The imprint of this edition read Drukkerij J. H. Kok N.V. Te Kampen [without a date.] The other edition, published for commercial circulation, designated Kolff as Dr. W. J. Kolff on the title page and printed wrapper. Its imprint read Uitgaave J. H. Kok N.V.  Kampen- 1946. It did not include the sheet of "Stellingen."

Kolff translated the work into English as New ways of treating uraemia. The artificial kidney...London: Churchill, 1947.