Vieussens, professor at Montpellier, was the first to describe the centrum ovale correctly. The publication of the above work threw new light on the subject of the configuration and structure of the brain, spinal cord, and nerves. With numerous large folding copperplates, it is considered the best illustrated work on the nervous system published in the 17th century. Second issue, identical except dated 1685. Both issues have the words, “editio nova” on the title page. Digital facsimile of the 1584 issue from Google Books at this link.