The most complete and accurate account of the nervous system which had hitherto appeared, and the work that coined the term, “neurology". In its preparation Willis was helped by his students Richard Lower and Thomas Millington, and its illustrations are by the architect, Sir Christopher Wren, making this one of the earliest scientific collaborations in England. Willis’s classification of the cerebral nerves held the field until the time of Soemmerring. The book includes (Cap. I and plates 1, 2) the description of the “circle of Willis”, and of the eleventh cranial nerve (“nerve of Willis”). Willis recognized the sympathetic system and accepted the brain as the organ of thought. English translation by S. Pordage, 1681. The anatomy of the brain and nerves. Tercententary edition, ed. by W. Feindel, 2 vols, Montreal, 1965, reprints this translation with a complete annotated bibliography of the work. Wepfer (No. 2703) and others preceded Willis in giving a detailed and complete description of the “circle of Willis”.