The first systematic treatise on pathology, which also introduced the names for the sciences of pathology and physiology. In the second part, entitled “Pathologia”, Fernel provided the first systematic essay on the subject, methodically discussing the diseases of each organ. Fernel was the first to describe appendicitis, endocarditis, etc. He believed aneurysms to be produced by syphilis, and differentiated true from false aneurysms. He was physician to Henri II of France. The first section of the above work is the second edition of Fernel’s classic treatise on physiology (No. 572).