Paré’s first general treatise on surgery, and the most comprehensive of his treatises before his collected works (1575). Dix livres included Paré's first description of the use of the ligature in amputations, one of his greatest contributions. Paré began the work with an exposition of his method of treating gunshot wounds, including descriptions and illustrations of the instruments he used. In his second chapter he discussed the treatment of arrow wounds, reminding us that arrows were still a major weapon of war in the 16th century. In his third chapter he discussed his methods of treating fractures, and the instruments, splints, and bandaging methods required. His fourth book covered the treatment of contusions, and the use of many instruments. His fifth book concerned the treatment of burns. The sixth book concerned what he called  "caries of the bones" which caused ulceration and putrefaction. These wounds he often treated with cautery. The seventh book concerned gangrene and "mortification," their treatment by amputation, and prostheses which Paré designed for these patients, including artificial legs and artificial hands. In his eighth book Paré discussed urological diseases including surgery for urinary stricture The ninth book concerned surgery for kidney and bladder stones. The tenth book further discussed urological problems, followed by a long section in which Paré illustrated and described the widest range of his instruments and the uses for each.

Paré also had an extensive dental practice and his books contain much information on the subject. He designed several instruments for extracting teeth, including an extraction forceps for breaking and pulling the teeth, sponge obturators, and an obturator with screw closure and special forceps for placement. He described a variety of pelican which he called a daviet. He also described and illustrated artificial teeth made of bone which he attached by silver wire. English translation as Ten books of surgery with the magazine of the instruments necessary for it. Athens, Georgia: University of Georgia Press, 1969. See No. 55. Digital facsimile of the 1575 edition from BnF Gallica at this link