An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #9047

  • 6883

DNA sequencing with chain-terminating inhibitors.

Proc. Nat. Acad. Sci., 74, 5463-5467, 1977.

Sanger and colleagues developed methods for rapid sequencing of long sections of DNA molecules. Sanger’s method, and that developed by Gilbert and Maxam, made it possible to read the nucleotide sequence for entire genes that ran from 1000 to 30,000 bases long. With S. Nicklen and A. R. Coulson. This paper is available from the PNAS at this link.

In 1980 Sanger shared half of the Nobel Prize in Chemistry with Walter Gilbert "for their contributions concerning the determination of base sequences in nucleic acids." The other half was awarded to Paul Berg "for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA."



Subjects: BIOLOGY › MOLECULAR BIOLOGY, BIOLOGY › MOLECULAR BIOLOGY › Genomics, NOBEL PRIZES › Nobel Prize in Chemistry (selected)
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