Jacobs was the first woman in the Netherlands to graduate from medical school. In 1882 she founded the first birth control clinic in the Netherlands and "the first clinic in the world devoted solely to dissemtinating information on the topic" (Wikipedia). This was a popular work on woman's health illustrated with color plates with movable flaps.

See Jacobs, Memories: My life as an international leader in health, suffrage, and peace. Edited by Harriet Feinberg. Translated by Annie Wright. Historical afterward by Harriet Pass Freidenreich. Literary afterward by Harriet Feinberg. New York: Feminist Press at CUNY, 1996.