LWOFF, André Michel
2 entries
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Conditions de l'efficacité inductice du rayonnement ultra-violet chez une bactérie lysogène.Ann. Inst. Pasteur, 81, 370-389, 1951.Lwoff successfully explained how the process of lysogeny works. The bacteriophage’s genes are incorporated into the bacteria’s genetic material, but remain latent until a trigger factor causes a new phage to be formed. Lwoff also showed that ultraviolet light can be a trigger factor. See also Lwoff's "Lysogeny," Bacteriological Reviews, 17 (1953) 269-337. Digital facsimile of Lysogeny from PubMedCentral at this link. Subjects: BACTERIOLOGY › Lysogeny |
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Rôle des cations bivalents dans l'induction du développement du prophage par les agents reducteurs.C. R. Acad. Sci. (Paris), 234, 366-368, 1952.
Lwoff gave the name "prophage" to the form in which the genome of the bacteriophage is perpetuated in lysogenic bacteria. The bacteriophages produced by these bacteria, known as temperate bacteriophages, can therefore follow one of two pathways when they infect sensitive bacteria. Either, like virulent bacteriophages, they multiply in the bacteria which lyse releasing infectious bacteriophages, or their genome is incorporated into the bacteria that they perpetuate in non-infectious form, the prophage. In 1965 Lwoff shared the Nobel Prize in Physiology or Medicine with François Jacob and Jacques Monod "for their discoveries concerning genetic control of enzyme and virus synthesis." Subjects: BACTERIOLOGY › Lysogeny, NOBEL PRIZES › Nobel Prize in Physiology or Medicine |