BEST, Charles Herbert
|
The internal secretion of the pancreas.J. Lab. clin. Med., 7, 251-66, 1921 – 1922.This paper reports the isolation of insulin. An extract from the pancreas of a dog, removed after ligation of the excretory duct, was found to exercise a reducing influence on the percentage of sugar in the blood. Digital facsimile from insulin.library.utoronto.ca at this link. Subjects: Ductless Glands: Internal Secretion › Pancreas, HEPATOLOGY, Metabolism & Metabolic Disorders › Diabetes |
|
The internal secretion of the pancreas. (Abstract).Amer. J. Physiol., 59, 479, 1922.A preliminary one-page communication regarding the isolation of insulin, made to a meeting of the American Physiological Society in December 1921. Digital facsimile from insulin.library.utoronto.ca at this link. Subjects: Metabolism & Metabolic Disorders › Diabetes, NOBEL PRIZES › Nobel Prize in Physiology or Medicine |
|
Pancreatic extracts in the treatment of diabetes mellitus.Canad. med. Ass. J., 12, 141-46, 1922.The first clinical application of insulin in the treatment of diabetes. Co-authored by W. R. Campbell, and A. A. Fletcher. Digital facsimile from PubMedCentral at this link. Subjects: Metabolism & Metabolic Disorders › Diabetes |
|
The nature of the vaso-dilator constituents of certain tissue extracts.J. Physiol. (Camb.), 62, 397-417, 1927.Proof that histamine occurs in certain organs in amounts sufficient to account for the depressant action of extracts of these organs. With H. H. Dale, H. W. Dudley, and W. V. Thorpe. Subjects: PHARMACOLOGY › PHARMACEUTICALS › Cardiovascular Medications |
|
Heparin and the thrombosis of veins following injury.Surgery, 2, 163-87, 1937.Order of authorship in the original publication: Murray, Jaques, Perrett, Best. Heparin was discovered by Jay McLean and William Henry Howell in 1916; however it was not tested as an anticoagulant in clinical trials until 1935. With L.B. Jaques, T. S. Perrett. Subjects: HEMATOLOGY › Anticoagulation, VASCULAR SURGERY |