Gagliardi, a papal physician, fiirst described the lamellar structure of the bones.  He also carried out some tests and comparative research between human and calf bones, and probably first described a case of bone tuberculosis. The work includes research and illustrations on the structure of teeth.  Gagliardi was also reputed to have been the first to describe the tooth enamel in detail. According to Desirabode, he obtained sparks from tooth enamel "by hitting them with steel".
Digital facsimile from Google Books at this link.