The most widely disseminated of all plague tracts from the time of the Black Death, of which 33 printed editions appeared in the 15th century. A French rhymed version appeared in 1476, but this version is very different from the prose, and from the pre-printing manuscripts that are known. The plague tracts from the Black Death represent the first productions of a large-scale public health effort in Europe. ISTC No. ij00015000. Digital facsimile from the Bayerische Staatsbibliothek at this link.

The earliest medical work printed in English. It was published without printer's name or date, but has been attributed to the press of William Machlinia, in London, and estimated to have been published in 1483."Although often attributed in incunable editions to Benedictus Kamisius, Kamintus, Canutus or Kanuti (i.e. Bengt Knutsson, bishop of Västerâs), the author is probably Johannes Jacobi (i.e. Jean Jasme or Jacme) (Wickersheimer)" (ISTC no.  ij00013200). J. F. Payne, "The Earliest Medical Work Printed in English", British Medical Journal v.1 [1480]; May 11, 1889, 1085-86.