KING, Mary-Claire
1 entries
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Linkage of early-onset familial breast cancer to Chromosome 17q21.Science, 250, 1684-1689, 1990.King showed that breast cancer can be inherited due to mutations in the Breast cancer type 1 susceptibility protein, a protein that in humans is encoded by the BRAC1 gene. BRCA1 is a human tumor suppressor gene (also known as a caretaker gene) that is responsible for repairing DNA. Subjects: GENETICS / HEREDITY › HEREDITARY / CONGENITAL DISEASES OR DISORDERS › Hereditary Cancers › Breast Cancer 1 & 2, ONCOLOGY & CANCER › Carcinoma |