DELBRÜCK, Max
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Ueber die Natur der Genmutation und der Genstruktur.Nachr. Ges. Wiss. Göttíngen, math.-fis. Kl., Fachgr. 6, 1, 189-245, 1935.This paper is divided into four sections. The first, by Timofeev-Ressovskij, describes the mutagenic effects of x-rays and gamma rays on Drosophila melanogaster; the second part, by Zimmer, analyzes Timofeev-Ressovskij's results theoretically. The third and most remarkable section, by Delbrück, puts forth a model of genetic mutation based on atomic physics. It represents Delbrück's debut in biology. This has been called the “green paper”, referring to the color of the paper cover of the Nachrichten, and also the Dreimännerarbeit of genetics, for the three authors involved. This paper provided much of the material for Erwin Schrodinger's What is life? (1944), a work that takes a "naive physicist's" approach to the problems of heredity and variation; Shrodinger's book is often cited as having inspired Watson, Crick, Wilkins and others to focus their careers on the problems of molecular biology.
Subjects: BIOLOGY › MOLECULAR BIOLOGY, GENETICS / HEREDITY |
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Electron microscope studies of bacterial viruses.J. Bacteriol., 46, 57-76, 1943.This work demonstrated the absorption of the phages on the host cell, and the lysis of the host cell and the liberation of a hundred or so daughter paritcles from each cell. It also showed that the particles multiply inside the cells rather than at their surfaces, since unti lysis occurs the number of particles visible at the surface remains constant. Subjects: IMAGING › Photography / Photomicrography , VIROLOGY › Bacteriophage |
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Induced mutations in bacterial viruses.Cold Spring Harbor Symp. quant. Biol., 11, 33-37, 1946.Genetic recombination in bacteriophages. Subjects: BIOLOGY › MOLECULAR BIOLOGY, NOBEL PRIZES › Nobel Prize in Physiology or Medicine , VIROLOGY, VIROLOGY › Bacteriophage |