Louis’ researches were based on 358 dissections and 1,960 clinical cases, and included a numerical study of extra-pulmonary lesions. First edition in English, London, 1835. English translation, Boston, 1836. A translation of the 2nd edition was published by the Sydenham Society in 1844.

Louis introduced the term “typhoid fever” in reference to the disturbed mental condition of the patient; he first described the lenticular rose spots. His book established the pathological picture of the disease. English translation, Boston, 1836.

Louis refuted Broussais’s system of medicine, his “médicine physiologique.”  Louis was instrumental in establishing medicine as an exact science by the introduction of the numerical or statistical method. English translation by C. G. Putnam, with preface and appendix by James Jackson as Researches on the effects of bloodletting in some inflammatory diseases, Boston, 1836.

The Translator's Introduction begins as follows: "The work now presented to the public has heretofore existed in manuscript only. Circumstances have delayed its publication in France, and some years may yet elapse before it appears in that country..."

Digital facsimile from the U.S. National Library of Medicine at this link.