An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2022 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

15961 entries, 13944 authors and 1935 subjects. Updated: March 22, 2024

KENDREW, Sir John Cowdery

3 entries
  • 6910

The computation of Fourier syntheses with a digital electronic calculating machine.

Acta Cryst., 5, 109-116, 19511952.

The first paper published in a scientific journal on the application of an electronic computer to computational biology. At the second English computer conference held in Manchester from July 9-12, 1951 computer scientist John Makepiece Bennett and biochemist and crystallographer John Kendrew described their use of the Cambridge EDSAC for the computation of Fourier syntheses in the calculation of structure factors of the protein molecule myoglobin. Their paper in Acta Crystallographica was an expansion of a briefer summary published in the Manchester University Computer Conference Proceedings (1951). It represents a more thorough presentation intended for x-ray crystallographers, and must have been submitted almost immediately after the Manchester Conference, since it was received by Acta Crystallographica on July 28, 1951.



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Structure, COMPUTING/MATHEMATICS in Medicine & Biology
  • 6911

A three-dimensional model of the myoglobin molecule obtained by x-ray analysis.

Nature, 181, 662-666, 1958.

Initial paper on the first solution of the three-dimensional molecular structure of a protein, for which Kendrew shared the 1962 Nobel Prize in chemistry with Max Perutz. Computing the molecular structure in 3 dimensions was possible through the use of the Cambridge EDSAC stored-program electronic computer. Co-authored by G. Bodo, R. G. Parrish, H. Wyckoff, and D. C. Phillips. For further information see the entry at HistoryofInformation.com at this link.



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Structure, COMPUTING/MATHEMATICS in Medicine & Biology
  • 6912

Structure of myoglobin: A three-dimensional Fourier synthesis at 2 Å resolution.

Nature, 185, 422-27, 1960.

Kendrew's second paper reporting the first solution of the three-dimensional molecular structure of a protein, for which he shared the 1962 Nobel Prize in chemistry with Max Perutz, who solved the structure of the related and more complex protein, hemoglobin, two years after Kendrew’s achievement. With R. E. Dickerson, B. E. Strandberg, R. G. Hart, D. R. Davies, D. C. Phillips, and V. C. Shore.



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Structure, COMPUTING/MATHEMATICS in Medicine & Biology