An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #14874

  • 12633

The total synthesis of penicillin V.

J. Amer. chem. Soc., 29, 1262-1263, 1957.

Sheehan and Henery-Logan reported the step by step synthesis of penicillin V (phenoxymethylpenicillin) and the cyclization of the beta lactam ring, key to creation of beta-lactam antibiotics.

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: PHARMACOLOGY › PHARMACEUTICALS › Antibiotics, PHARMACOLOGY › PHARMACEUTICALS › Antibiotics › Penicillin
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