An Interactive Annotated World Bibliography of Printed and Digital Works in the History of Medicine and the Life Sciences from Circa 2000 BCE to 2024 by Fielding H. Garrison (1870-1935), Leslie T. Morton (1907-2004), and Jeremy M. Norman (1945- ) Traditionally Known as “Garrison-Morton”

16061 entries, 14144 authors and 1947 subjects. Updated: December 10, 2024

Permanent Link for Entry #16497

  • 14182

Three-dimensional model of purple membrane obtained by electron microscopy.

Nature, 257, 28-32, 1975.

The invention of Cryogenic electron microscopy (cryo-EM). The novel technique was achieved by "by applying the method to tilted specimens, and using the principles put forward by De Rosier and Klug (GM - 13935), for  the combination of a three-dimensional map of the membrane at 7 Angstroms resolution.”

In 2017 Henderson shared the 2017 the Nobel Prize in Chemistry with Jacques Dubochet and Joachim Frank "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution."

(Thanks to Juan Weiss for this reference and its interpretation.)



Subjects: BIOLOGY › MOLECULAR BIOLOGY › Protein Structure, Microscopy › Cryogenic electron microscopy, NOBEL PRIZES › Nobel Prize in Chemistry (selected)
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